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Generic Name: phentermine (FEN ter meen) Brand names: DISEBSIN TERFAMEX. Phentermine: Clinical Pharmacology Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines.

Actions include central nervous system stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which the sephenomena have been looked for.

Phentermine used in obesity are commonly known as anorecticsor anorexigenics It has not been established that the action of such drugs in treating obesity is primarily one of appetite suppression. Other central nervous system actions, or metabolic effects, may be involved, for example.

Adult obese subjects instructed in dietary management and treated with anorecticdrugs lose more weight on the average than those treated with placebo and diet, as determined in relatively short-term clinical trials.

Phentermine: Uses Oral Phentermine hydrochloride is used as an appetite suppressant used for short-term treatment of exogenous obesity. Phentermine is used in conjunction with an overall diet plan to reduce weight.

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Phentermine: How it Works Phentermine works by stimulating a gland, called the hypothalamus, and affecting certain neurotransmitters to decrease appetite. Because Phentermine hydrochloride is similar chemically to amphetamines, it has the potential for psychological dependency.

Phentermine should be used with caution. Phentermine: How to Take Phentermine is best taken on an empty stomach one half-hour before breakfast. Because Phentermine may cause sleeplessness, avoid taking a dose late in the day.

Take Phentermine as prescribed. Do not take it more often or longer than directed. Phentermine: Side Effects Dry mouth, sleeplessness, irritability, stomach upset or constipation may occur the first few days as your body adjusts to Phentermine.

If these effects persist or become bothersome, inform your doctor. Phentermine: Dosage Adults Under 60: Capsules: Phentermine 15 to 37.5 mg every morning before breakfast or 1 to 2 hours after breakfast.

Tablets: Phentermine 15 to 37.5 mg every morning before breakfast or 1 to 2 hours after breakfast. Alternatively, take Phentermine 15 to 37.5 mg in divided doses one-half hour before meals. Adults 60 and Over: Reduced Phentermine dosage may be necessary. Consult your physician.

Infants and Children: Use is not recommended. Maximum Dosage Recommendations: Do not exceed the recommended Phentermine doses, unless deemed necessary by your doctor. If You Miss a Dose: Take as soon as possible. If close to the next dose, skip and take the next dose.

Do not double the dose. Phentermine: Precautions Tell your doctor your complete medical history especially if you have high blood pressure, an over-active thyroid, glaucoma, diabetes or emotional problems. Consult with your doctor if you think you are pregnant or before breast-feeding.

Alcohol can increase unwanted side effects of dizziness. Limit alcohol use. Phentermine is not recommended for use in children. Consult your doctor or pharmacist for further information.